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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-miR-183
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line human RB samples and normal retina tissues; human RB cell lines Y79, SO-RB50 and WERI-RB1
Methods transfection, Western blot, luciferase reporter assay, flow cytometry
Expression pattern down-regulated
Functional description miR-183 targets and downregulates LRP6 in the growth, migration and invasion of RB cells.
PubMed ID 24289859
Year 2014
Title MicroRNA-183 suppresses retinoblastoma cell growth, invasion and migration by targeting LRP6.
Drug-related ncRNA NO

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